What is the most important information I should know about Theo-24?

• Do not crush or chew any extended-release formulation of Theo-24. Swallow the medication whole. It is specially formulated to release slowly in the body. If you do not know whether your medication is an extended-release formulation, ask your pharmacist.
• Call your doctor right away if you experience nausea, vomiting, insomnia, restlessness, seizures, an increased heart rate, or a headache. These could be signs of too much Theo-24 in the blood.
• Do not start or stop smoking without first talking to your doctor. Smoking changes the way the body uses Theo-24, and a dosage adjustment may be necessary.
• Do not take more of this medicine than is prescribed without consulting your doctor. Seek medical attention if you are having increasing difficulty breathing.

What is Theo-24?

• Theo-24 is a bronchodilator. Theo-24 works in several ways: it relaxes muscles in the lungs and chest to allow more air in, it decreases the sensitivity of the lungs to allergens and other substances that cause inflammation, and it increases contractions of the diaphragm to draw more air into the lungs.
• Theo-24 is used to treat the symptoms of asthma, bronchitis and emphysema.
• Theo-24 may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking Theo-24?

• Before taking Theo-24, tell your doctor if you have
  • a stomach ulcer;
  • seizures;
  • high blood pressure, a heart condition, or any type of heart disease;
  • fluid in the lungs;
  • a thyroid condition;
  • liver disease; or
  • kidney disease.
• You may not be able to take Theo-24, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• Theo-24 is in the FDA pregnancy category C. This means that it is not known whether Theo-24 will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant.
• Theo-24 passes into breast milk and may affect a nursing baby. Do not take Theo-24 without first talking to your doctor if you are breast-feeding a baby.
• If you are over 60 years of age, you may be more likely to experience side effects from Theo-24. Your doctor may prescribe a lower dose of this medication.

How should I take Theo-24?

• Take Theo-24 exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• You can take Theo-24 with food to lessen stomach upset.
• Take doses of Theo-24 at the same time every day whenever possible to keep a constant level of the medication in the blood.
• Do not crush or chew any extended-release formulation of Theo-24. Swallow the medication whole. It is specially formulated to release slowly in the body. If you do not know whether your medication is an extended-release formulation, ask your pharmacist.
• Some formulations may be sprinkled over soft food such as pudding or applesauce and then eaten. Talk to your doctor about other formulations of Theo-24 if you have difficulty swallowing.
• Shake the liquid forms of Theo-24 well before use. To ensure that you get a correct dose, measure the liquid with a dose-measuring cup or spoon, not a regular table spoon. If a spoon or cup is not provided with the medication and you do not have one, ask your pharmacist where you can get one.
• Do not change the brand, generic form, or formulation (tablet, capsule, liquid) of Theo-24 that you are taking without first talking to your doctor. Some forms of Theo-24 are interchangeable while others are not.
• Store Theo-24 at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication.

What happens if I overdose?

• Seek emergency medical attention.
• Symptoms of a Theo-24 overdose include nausea, vomiting, headache, insomnia, tremor (shaking hands or twitching), restlessness, seizures, and irregular heartbeats.

What should I avoid while taking Theo-24?

• Use caution when driving, operating machinery, or performing other hazardous activities. Theo-24 may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
• Do not start or stop smoking without first talking to your doctor. Smoking changes the way the body uses Theo-24, and a change in dosage may be necessary.
• Do not change the brand, generic form, or formulation (tablet, capsule, liquid) of Theo-24 that you are taking without first talking to your doctor. Some forms of Theo-24 are interchangeable while others are not.
• Avoid eating excessive amounts of grilled or char-broiled foods. Doing so may change the dose of Theo-24 needed to control your symptoms.
• Avoid excessive consumption of caffeinated beverages or foods such as coffee, tea, cola, and chocolate. Theo-24 is related chemically to caffeine, and side effects may be experienced if large amounts of caffeine are consumed.

What are the possible side effects of Theo-24?

• If you experience any of the following serious side effects, stop taking Theo-24 and seek emergency medical attention or contact your doctor immediately:
  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • seizures;
  • increased or irregular heartbeats; or
  • severe nausea or vomiting.
• Other, less serious side effects may occur although they are not common at appropriate doses. Continue to take Theo-24 and talk to your doctor if you experience
  • slight nausea, decreased appetite, or weight loss;
  • restlessness, tremor, or insomnia; or
  • headache, lightheadedness, or dizziness.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Theo-24?

• Theo-24 interacts with many other drugs. Tell your doctor and pharmacist about all other medications you are taking, including herbal remedies, vitamins, and other nonprescription items.
• The following drugs may increase the level of Theo-24 in the blood, possibly leading to side effects:
  • alcohol;
  • cimetidine (Tagamet, Tagamet HB);
  • fluoroquinolone antibiotics such as enoxacin (Penetrex), lomefloxacin (Maxaquin), ciprofloxacin (Cipro), norfloxacin (Noroxin), and ofloxacin (Floxin);
  • clarithromycin (Biaxin) and erythromycin (Ery-Tab, E.E.S., E-Mycin, others);
  • disulfiram (Antabuse);
  • estrogens (Ogen, Premarin, and many other types);
  • fluvoxamine (Luvox);
  • methotrexate (Folex, Rheumatrex);
  • mexiletine (Mexitil) and propafenone (Rythmol);
  • rofecoxib (Vioxx);
  • propranolol (Inderal);
  • tacrine (Cognex);
  • ticlopidine (Ticlid); and
  • verapamil (Verelan, Calan, Isoptin).
• The following drugs may decrease Theo-24 levels in the blood, possibly leading to loss of effectiveness of the medication:
  • aminoglutethimide (Cytadren);
  • carbamazepine (Tegretol);
  • isoproterenol (Isuprel);
  • moricizine (Ethmozine);
  • phenobarbital (Luminal, Solfoton);
  • phenytoin (Dilantin);
  • rifampin (Rifadin); and
  • sucralfate (Carafate).
• Drugs other than those listed here may also interact with Theo-24 or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.